Late pregnancy thyroid-binding globulin predicts perinatal depression

Perinatal risks of untreated depression during pregnancy.

OBJECTIVE To review the literature on the perinatal risks involved in untreated depression during pregnancy. METHOD We searched Medline and medical texts for all studies pertaining to this area up to the end of April 2003. Key phrases entered were depression and pregnancy, depression and pregnancy outcome, and depression and untreated pregnancy. We did not include bipolar depression. RESULT...

Primary thyroid failure with concomitant thyroxine binding globulin deficiency.

Free thyroid hormone index, thyroid hormone/thyroxin-binding globulin ratio, triiodothyronine uptake, and thyroxin-binding globulin compared for diagnostic value regarding thyroid function.

The thyroid hormone/thyroxin-binding globulin (TBG) ratio and the free thyroid hormone index (FTI) were compared in 372 subjects classified according to age, sex, and biochemical and clinical findings. Age-related variations in thyroid function tests were investigated, as was the relationship between triiodothyronine uptake and TBG. Men, but not women, showed significant age-dependent changes i...

Iron deficiency predicts poor maternal thyroid status during pregnancy.

CONTEXT Pregnant women are often iron deficient, and iron deficiency has adverse effects on thyroid metabolism. Impaired maternal thyroid function during pregnancy may cause neurodevelopmental delays in the offspring. OBJECTIVE Our objective was to investigate whether maternal iron status is a determinant of TSH and/or total T(4) (TT4) concentrations during pregnancy. DESIGN AND OUTCOME MEA...

Perinatal depression

depression is a signifi cant mental and public health problem and may be one of the most disabling disorders among women of childbear-ing age. 1 Perinatal depression is associated with a multitude of negative sequelae for women, children, and families, including poor maternal-fetal attachment, adverse neona-tal outcomes (low birth weight, preterm birth, small for gestational age), poor infant a...